Vinblastine
- IVVinblastine
Mechanism of Action
- Inhibits cell proliferation by preventing polymerization of tubulin into microtubules.
Clinical Use
Indications
- Certain solid organ and haematologic malignancies, as guided by cancer specialists and local guidelines.
- Adverse Effects
- Neurotoxicity - numbness / paraesthesia / weakness
- Leukopaenia / anaemia / thrombocytopaenia
- Nausea / vomiting / constipation / paralytic ileus
- Alopecia