- Mechanism of Action
- Inhibits cell proliferation by preventing polymerization of tubulin into microtubules.
Clinical Use
- Indication
- Certain solid organ and haematologic malignancies, as guided by cancer specialists and local guidelines.
- Adverse Effects
- Neurotoxicity – numbness / paraesthesia / weakness
- Leukopaenia / anaemia / thrombocytopaenia
- Nausea / vomiting / constipation / paralytic ileus
- Alopecia
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