Drug Guide
 

Vecuronium

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    IV
    Vecuronium
    6-8x more potent than rocuronium
    Onset 3 minutes
    Duration 30 minutes
    • Mechanism of Action
    • Competitively inhibits the action of acetylcholine on postsynaptic nicotinic receptors, preventing acetylcholine-mediated muscle contraction.

Clinical Use

    • Indications
    • Relaxation of skeletal muscle for anaesthesia during surgery
    • Relaxation of skeletal muscle to facilitate mechanical ventilation in ICU patients
    • Adverse Effects
    • Hypersensitivity reactions – flushing, rash, bronchospasm, anaphylaxis
    • Transient hypotension
    • Tachycardia / bradycardia
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