Ustekinumab
- Subcut / IVUstekinumabStelara
- Mechanism of Action
- A human monoclonal antibody directed against p40, a shared subunit present in both IL-12 and IL-23. Inhibition of IL-12 results in reduced differentiation of TH1 cells, while inhibition of IL-23 results in reduced induction of TH17 cells.
Clinical Use
- Indications
- Adverse Effects