Login or Register to unlock everything MedSchool has to offer!

#

A

B

C

D

E

F

G

H

I

K

L

M

N

O

P

Q

R

S

T

U

V

W

Z

 

Urokinase

  •  
    IV
    Urokinase
    Abbokinase 
    • Mechanism of Action
    • Activates plasminogen, resulting in its activation to plasmin and thus fibrinolysis.

Clinical Use

    • Indication
    • Pulmonary embolism with haemodynamic compromise, or massive pulmonary embolism.
    • Contraindications
    • Active bleeding
    • Recent GI / urinary bleeding
    • Recent major trauma / surgery
    • Recent ischaemic stroke
    • Intracranial haemorrhage, aneurysm, AVM or neoplasm
    • Current anticoagulant use
    • Pregnancy
    • Adverse Effects
    • Life-threatening haemorrhage
    • Hypersensitivity – rash, oedema, anaphylaxis
    • Cardiac arrhythmia
    • Hypotension

Potential Indications
BETA

Pulmonary Embolus

Associated Adverse Effects
BETA

Anaphylaxis
Anaphylaxis
Feedback