Oral / IV
Tranexamic Acid
Cyklokapron
- Mechanism of Action
- Blocks lysine binding sites on plasminogen, preventing its conversion to plasmin and thus preventing fibrinolysis.
Clinical Use
- Indications
- Reduction in blood loss post total hip / knee arthroplasty
- Menorrhagia
- Contraindications
- History of / high risk of / active thrombosis
- Subarachnoid haemorrhage
- Adverse Effects
- Nausea / vomiting / diarrhoea
- Change in colour vision
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