- IV / OralTramadolTramal
Mechanism of Action
- Synthetic weak μ opioid agonist, and also inhibits nociception through enhancement of noradrenergic and serotonergic pathways.
- Between 1-10% of patients lack the enzyme required to convert it to its active form - in these patients tramadol will have less of an effect.
- Less likelihood of tolerance, low potential for abuse than opioids.
- Acute and chronic pain.
- Adverse Effects
- Dry mouth
- Nausea / vomiting