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Drug Guide
 
 

Tramadol

 
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    IV / Oral
    Tramadol
    Tramal 
  • Mechanism of Action

  •  Synthetic weak µ opioid agonist, and also inhibits nociception through enhancement of noradrenergic and serotonergic pathways.
  • Pharmacology
  • Between 1-10% of patients lack the enzyme required to convert it to its active form – in these patients tramadol will have less of an effect.
  • Less likelihood of tolerance, low potential for abuse than opioids.

Clinical Use

  • Indications

  • Acute and chronic pain.
  • Adverse Effects
  • Dizziness
  • Sweating
  • Dry mouth
  • Nausea / vomiting
  • Constipation
  • Fatigue
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