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Tramadol

  •  
    IV / Oral
    Tramadol
    Tramal 
    • Mechanism of Action
    •  Synthetic weak µ opioid agonist, and also inhibits nociception through enhancement of noradrenergic and serotonergic pathways.
    • Pharmacology
    • Between 1-10% of patients lack the enzyme required to convert it to its active form – in these patients tramadol will have less of an effect.
    • Less likelihood of tolerance, low potential for abuse than opioids.

Clinical Use

    • Indication
    • Acute and chronic pain.
    • Adverse Effects
    • Dizziness
    • Sweating
    • Dry mouth
    • Nausea / vomiting
    • Constipation
    • Fatigue
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