- Mechanism of Action
- Inhibits voltage-gated sodium channels and enhances GABA-mediated inhibition, resulting in suppression of seizure activity.
Clinical Use
- Indications
- Second-line therapy for partial (focal) seizures
- Migraine prophylaxis
- Adverse Effects
- CNS disturbances – drowsiness, dizziness / ataxia, diplopia, tremor, cognitive slowing
- Nausea / vomiting
- Weight loss
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