×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Tofacitinib

 
Bookmark
 View Topic Outline
  •  
    Oral
    Tofacitinib
    Xeljanz 
     
    Inhibits JAK1, JAK2 and JAK3
    • Mechanism of Action
    • Inhibits Janus Kinases (JAK1, JAK2 and JAK3), a group of non-receptor tyrosine kinases involved in signalling downstream to cytokine receptors in immune and haematopoietic cells.

Clinical Use

    • Indication
    • Moderate to severe rheumatoid arthritis refractory to methotrexate.
    • Adverse Effects
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now