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Drug Guide
 
 

Tocilizumab

 
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    IV / Subcut
    Tocilizumab
    Actemra 
  • Mechanism of Action

  • A humanised monoclonal antibody that binds to and inhibits IL-6 receptors, resulting in reduced IL-6 binding and a reduction in acute inflammation.

Clinical Use

  • Indications
  • Severe rheumatoid arthritis
  • Giant cell arteritis
  • Severe juvenile idiopathic arthritis
  • Adverse Effects
  • Injection site reactions
  • Infections (particularly upper respiratory tract infections)
  • Headache
  • Hypertension
  • Diarrhoea
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