Tocilizumab
- IV / SubcutTocilizumabActemra
Mechanism of Action
- A humanised monoclonal antibody that binds to and inhibits IL-6 receptors, resulting in reduced IL-6 binding and a reduction in acute inflammation.
Clinical Use
- Indications
- Severe rheumatoid arthritis
- Giant cell arteritis
- Severe juvenile idiopathic arthritis
- Adverse Effects
- Injection site reactions
- Infections (particularly upper respiratory tract infections)
- Headache
- Hypertension
- Diarrhoea