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Tiotropium

 
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  •  
    MDI
    Tiotropium
    Spiriva 
     
    Long-acting - best for COPD maintenance

  • Mechanism of Action

  • Inhibits muscarinic (M3) receptors, leading to bronchial smooth muscle relaxation and bronchodilation through reduction in acetylcholine-mediated vagal tone.

Clinical Use

  • Indications
  • Acute asthma (ipratropium)
  • Acute exacerbations of COPD (ipratropium)
  • Maintenance therapy for COPD (tiotropium)
  • Adverse Effects
  • Dry mouth
  • Headache
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