- MDITiotropiumSpirivaLong-acting â€“ best for COPD maintenance
Mechanism of Action
- Inhibits muscarinic (M3) receptors, leading to bronchial smooth muscle relaxation and bronchodilation through reduction in acetylcholine-mediated vagal tone.
- Acute asthma (ipratropium)
- Acute exacerbations of COPD (ipratropium)
- Maintenance therapy for COPD (tiotropium)
- Adverse Effects
- Dry mouth