- OralThyroxineOroxine, EutroxigAdjust every 6-8 weeks according to TSH
Mechanism of Action
- Synthetic T4 is converted to T3 that binds to nuclear thyroid hormone receptors, inducing alterations in gene transcription and subsequent effects on metabolism.
- TSH-responsive thyroid tumours
- Myxoedema coma
- Adverse Effects
- Thyrotoxicosis – palpitations, tachycardia, tachypnoea, fever, anxiety, headache, poor concentration
- Nausea / vomiting / diarrhoea