Thyroxine | Drug Guide - MedSchool
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Thyroxine

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    Oral
    Thyroxine
    Oroxine, Eutroxig 
     
    Adjust every 6-8 weeks according to TSH
    • Mechanism of Action
    • Synthetic T4 is converted to T3 that binds to nuclear thyroid hormone receptors, inducing alterations in gene transcription and subsequent effects on metabolism.

Clinical Use

    • Indications
    • Hypothyroidism
    • TSH-responsive thyroid tumours
    • Myxoedema coma
    • Adverse Effects
    • Thyrotoxicosis – palpitations, tachycardia, tachypnoea, fever, anxiety, headache, poor concentration
    • Nausea / vomiting / diarrhoea
 
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