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Teriparatide

  •  
    Subcut
    Teriparatide
    Forteo 
    • Mechanism of Action
    • Synthetic parathyroid hormone (PTH). Continuous PTH administration primarily stimulates osteoclast differentiation, while intermittent PTH administration (daily teriparatide) primarily stimulates osteoblast differentiation.
    • Indication
    • Severe post-menopausal osteoporosis or osteoporosis in males, that is refractory to other medications.
    • Contraindications
    • Paget’s disease of bone
    • Hypercalcaemia
    • Malignancy
    • Renal disease
    • Adverse Effects
    • Headache
    • Hypertension
    • Nausea / vomiting / diarrhea / constipation
    • Arthralgia
    • Dizziness
    • Osteosarcoma (in rats)
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