- Mechanism of Action
- Antagonises oestrogen receptors in breast tissue and agonises oestrogen receptors in endometrial tissue and bone.
Clinical Use
- Indication
- Endocrine therapy for ER positive breast cancer.
- Adverse Effects
- Hot flushes
- Vaginal bleeding
- Nausea / vomiting
- Headache
- Fluid retention
- Alopecia
- Deep venous thrombosis
- Endometrial cancer
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