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Tamoxifen

 
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  •  
    Oral
    Tamoxifen
    Genox 

  • Mechanism of Action

  • Antagonises oestrogen receptors in breast tissue and agonises oestrogen receptors in endometrial tissue and bone.

Clinical Use

  • Indications

  • Endocrine therapy for ER positive breast cancer.
  • Adverse Effects
  • Hot flushes
  • Vaginal bleeding
  • Nausea / vomiting
  • Headache
  • Fluid retention
  • Alopecia
  • Deep venous thrombosis
  • Endometrial cancer
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