• Mechanism of Action
• Inhibits T cell activation as well as transcription of IL-2 and other cytokines, through inhibition of calcineurin-mediated activation of NFAT.

Clinical Use

• • Indication
  • Prevention of graft rejection following kidney, liver or heart transplantation
• • Adverse Effects
• • Monitoring
  • Baseline and regular electrolytes, renal function, LFTs, FBC and lipids.