×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Suxamethonium / Succinylcholine

 
Bookmark
  •  
    IV / IM
    Suxamethonium / Succinylcholine

    • Mechanism of Action
    • Composed of two acetylcholine molecules joined at the acetate methyl group.
      Bind to nicotinic receptors, resulting in depolarization with opening of voltage-gated channels and muscle contraction. Voltage-gated sodium channels then close and are inactivated, while the membrane remains depolarized.
      Suxamethonium is not metabolized by acetylcholinesterase and therefore membrane depolarization is prolonged, resulting in prolonged inactivation of sodium channels and muscle relaxation.
      As the membrane remains depolarized, no further acetylcholine molecules are able to produce further depolarization.
    • Pharmacology

Clinical Use

    • Indications
    • Contraindications
    • Adverse Effects
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now