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Drug Guide
 
 

Sulfasalazine

 
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    Oral
    Sulfasalazine
    Salazopyrin 
     
    Not absorbed well – therefore most effective within the gut
    • Mechanism of Action
    • Inhibits 5-aminoimidazole-4-carboxamidoribonucleotide (AICAR) transformylase, which results in increased adenosine release at the inflamed site. Adenosine binds to A2 receptors on inflammatory cells resulting in reduced inflammation.

Clinical Use

    • Indications
    • Adverse Effects
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