Spironolactone | Drug Guide - MedSchool
Sign up to start your free trial of MedSchool Premium!Get Started
 
Drug Guide
 
 
#
A
B
C
D
E
F
G
H
I
K
L
M
N
O
P
Q
R
S
T
U
V
W
Z
 

Spironolactone

Bookmark
  •  
    Oral
    Spironolactone
    Aldactone, Spiractin 
    • Mechanism of Action
    • Inhibits the action of aldosterone on sodium-potassium exchange pumps in the distal convoluted tubule.
    • Pharmacology
    • Potassium-sparing diuretics.

Clinical Use

    • Indications
    • Refractory hypertension
    • Refractory heart failure
    • Peripheral oedema – due to congestive cardiac failure / renal failure / nephrotic syndrome / cirrhosis
    • Symptomatic ascites
    • Maintenance therapy for hypokalaemia
    • Primary aldosteronism
    • Hirsutism
    • Adverse Effects
    • Gynaecomastia
    • Nausea / vomiting / cramping / diarrhoea
    • Fatigue
    • Hyperkalaemia
 
Feedback