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Sitagliptin

 
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  •  
    Oral
    Sitagliptin
    Januvia 

  • Mechanism of Action

  • Stimulates insulin secretion by inhibiting dipeptidyl peptidase-4 (DPP-4), an enzyme that normally degrades incretin hormones.

  • Pharmacology

  • Stimulates insulin secretion in hyperglycaemia, and Inhibits glucagon secretion in hyperglucagonaemia.

Clinical Use

  • Indications

  • Glycaemic control for type II diabetes
  • Adverse Effects
  • URTI
  • Headache
  • Pancreatitis
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