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Simvastatin

  •  
    Oral
    Simvastatin
    Zocor 
    • Mechanism of Action
    • Inhibits HMG-CoA reductase, which acts as a catalyst in the production of cholesterol.

Clinical Use

    • Indications
    • Elevated low-density lipoprotein (LDL)
    • Secondary prevention of coronary artery / cerebrovascular / peripheral vascular disease / diabetes
    • Adverse Effects
    • Headache
    • Nausea / vomiting / diarrhea / flatulence
    • Elevated LFTs
    • Hyperglycaemia
    • Myalgia / arthralgia / rhabdomyolysis

Potential Indications
BETA

ST Elevation Myocardial Infarction
Non-ST Elevation Myocardial Infarction
Peripheral Vascular Disease
Ischaemic Stroke
Secondary Hyperlipidaemia

Associated Adverse Effects
BETA

Rhabdomyolysis
Rhabdomyolysis
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