- Mechanism of Action
- Inhibits HMG-CoA reductase, which acts as a catalyst in the production of cholesterol.
Clinical Use
- Indications
- Elevated low-density lipoprotein (LDL)
- Secondary prevention of coronary artery / cerebrovascular / peripheral vascular disease / diabetes
- Adverse Effects
- Headache
- Nausea / vomiting / diarrhea / flatulence
- Elevated LFTs
- Hyperglycaemia
- Myalgia / arthralgia / rhabdomyolysis
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