Saxagliptin

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    Oral
    Saxagliptin
    Onglyza 
     
    Reduce dose in renal insufficiency
    • Mechanism of Action
    • Stimulates insulin secretion by inhibiting dipeptidyl peptidase-4 (DPP-4), an enzyme that normally degrades incretin hormones.
    • Pharmacology
    • Stimulates insulin secretion in hyperglycaemia, and Inhibits glucagon secretion in hyperglucagonaemia.

Clinical Use

    • Indication
    • Glycaemic control for type II diabetes
    • Adverse Effects
    • URTI
    • Headache
    • Pancreatitis
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