- OralSaxagliptinOnglyzaReduce dose in renal insufficiency
Mechanism of Action
- Stimulates insulin secretion by inhibiting dipeptidyl peptidase-4 (DPP-4), an enzyme that normally degrades incretin hormones.
- Stimulates insulin secretion in hyperglycaemia, and Inhibits glucagon secretion in hyperglucagonaemia.
- Glycaemic control for type II diabetes
- Adverse Effects