Oral
Rosiglitazone
Avandia
- Mechanism of Action
- Activates peroxisome proliferator-activated receptor (PPAR), a nuclear receptor that regulates transcription of certain genes involved in glucose and lipid metabolism.
Clinical Use
- Indication
- Glycaemic control for severe type II diabetes.
- Contraindications
- Heart failure (past or present)
- Insulin
- Adverse Effects
- Headache
- URTI
- Myalgia
- Fluid overload
- Weight gain
- Increased risk of bladder cancer
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