Rosiglitazone | Drug Guide - MedSchool
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Rosiglitazone

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  •  
    Oral
    Rosiglitazone
    Avandia 
    • Mechanism of Action
    • Activates peroxisome proliferator-activated receptor (PPAR), a nuclear receptor that regulates transcription of certain genes involved in glucose and lipid metabolism.

Clinical Use

    • Indication
    • Glycaemic control for severe type II diabetes.
    • Contraindications
    • Heart failure (past or present)
    • Insulin
    • Adverse Effects
    • Headache
    • URTI
    • Myalgia
    • Fluid overload
    • Weight gain
    • Increased risk of bladder cancer
 
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