×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Rituximab

 
Bookmark
 View Topic Outline
  •  
    IV / Subcut
    Rituximab
    Mabthera 

  • Mechanism of Action

  • A monoclonal antibody that targets CD20, a transmembrane protein on the surface of B cells, resulting in antibody-dependent and complement-dependent cytotoxicity.

Clinical Use

  • Indications
  • Rheumatoid arthritis
  • Granulomatosis with polyangiitis (GPA)
  • Microscopic polyangiitis (MPA)
  • Non-Hodgkin lymphoma (NHL)
  • Chronic lymphocytic leukaemia (CLL)
  • Adverse Effects
  • Bone marrow suppression – leucopaenia, anaemia, thrombocytopaenia
  • Injection site reactions
  • Progressive multifocal leukoencephalopathy (PML)
  • Nausea / vomiting
  • Angioedema
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...