Drug Guide
 

Rimantadine

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    Oral
    Rimantadine
    Flumadine 
    • Mechanism of Action
    • Inhibit the ion channel function of M2 proteins on the viral membrane, preventing uncoating and disassembly of the virus once it enters cells.
    • Microbiology
    • Active against influenza A; no activity against influenza B.

Clinical Use

    • Indication
    • Influenza A prophylaxis.
    • Adverse Effects
    • Neuropsychiatric - dizziness, lethargy, ataxia, agitation, insomnia
    • Palpitations
    • Orthostatic hypotension
    • Dry mouth
    • Nausea / vomiting
    • Constipation
    • Livedo reticularis
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