×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Reteplase

 
Bookmark
  •  
    IV
    Reteplase
    Rapilysin 
  • Mechanism of Action

  • Binds to fibrin on the clot surface and activate plasminogen, resulting in its activation to plasmin and thus fibrinolysis.

Clinical Use

  • Indications

  • ST elevation myocardial infarction, within 12 hours of onset of chest pain
  • Contraindications
  • Active bleeding
  • Recent GI / urinary bleeding
  • Recent major trauma / surgery
  • Recent ischaemic stroke
  • Intracranial haemorrhage, aneurysm, AVM or neoplasm
  • Current anticoagulant use
  • Pregnancy
  • Adverse Effects
  • Life-threatening haemorrhage
  • Hypersensitivity – rash, oedema, anaphylaxis
  • Cardiac arrhythmia
  • Hypotension
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...