Drug Guide
 

Quinine

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    Oral / IV / IM
    Quinine
    Quinate 
    • Mechanism of Action
    • Believed to inhibit haem polymerisation, resulting in a buildup of toxic haem molecules into non-toxic haemozoin within the food vacuole of plasmodia.
    • Pharmacology
    • G-6-PD deficiency
    • Haemolytic anaemia

Clinical Use

    • Indication
    • Acute Plasmodium  falciparum infection
    • Contraindications
    • G-6-PD deficiency
    • Haemolytic anaemia
    • Adverse Effects
    • Cinchonism - tinnitus, deafness, headache, nausea / vomiting, visual disturbance
    • Hypersensitivity - rash, oedema
    • Hypoglycaemia
    • Haemolysis
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