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Drug Guide
 
 

Quinidine

 
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    Oral / IV
    Quinidine

    • Mechanism of Action
    • Binds to and inhibits fast sodium channels responsible for rapid depolarisation during phase 0 of the cardiomyocyte action potential.
    • Pharmacology
    • Acts on cardiomyocytes, with no action on pacemaker cells whose phase 0 is mediated by calcium influx. Moderate sodium channel blockade, but increases the absolute refractory period (ARP).

Clinical Use

    • Indications
    • Adverse Effects
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