- IVProtamine Sulfate
Mechanism of Action
- Binds to and inactivates heparin.
- 1mg of protamine sulfate is expected to neutralize 100 units of heparin, though smaller doses should be given depending on time elapsed since heparin administration.
- Reversal of heparin-associated bleeding
- Reversal of heparin preoperatively or after renal dialysis
- Adverse Effects
- Nausea / vomiting