MedSchool > Drugs > List
Login or Register to unlock everything MedSchool has to offer!
Full Drug List
 

#

A

B

C

D

E

F

G

H

I

K

N

O

P

Q

R

S

T

U

V

W

Z

 
 

Propylthiouracil

  •  
    Oral
    Propylthiouracil
    PTU
    • Mechanism of Action
    • Prevents utilization of iodine by the thyroid by inhibiting thyroperoxidase-catalysed iodination of tyrosine residues within the thyroid
      Suspected to have immunosuppressive effects by affecting signaling pathways between thyroid cells and T cells.
      Also inhibits conversion of T4 to T3.

Clinical Use

    • Indication
    • Hyperthyroidism, either as a sole agent or prior to surgery / radioiodine.
    • Adverse Effects
    • Rash
    • Neutropaenia / thrombocytopaenia
    • Liver failure
    • ANCA vasculitis

Potential Indications
BETA

Thyrotoxicosis
Feedback