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Primaquine

  •  
    Oral
    Primaquine
    Primacin 
    • Mechanism of Action
    • Unknown.
    • Microbiology
    • Effective against Plasmodium vivax and ovale as they enter a dormant phase in the liver.

Clinical Use

    • Indications
    • Elimination of intrahepatic Plasmodium vivax and ovale, once erythrocytic forms have been eradicated by a blood schizonticide.
    • Elimination of Plasmodium falciparum gametocytes, once erythrocytic forms have been eradicated by a blood schizonticide.
    • Contraindications
    • Pregnancy
    • G-6-P deficiency
    • Active rheumatoid arthritis or lupus
    • Adverse Effects
    • Nausea / vomiting
    • Haemolysis
    • Methaemoglobinaemia

Potential Indications
BETA

Plasmodium falciparum malaria
Plasmodium vivax malaria
Plasmodium ovale malaria
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