- Mechanism of Action
- Unknown.
- Microbiology
- Effective against Plasmodium vivax and ovale as they enter a dormant phase in the liver.
Clinical Use
- Indications
- Elimination of intrahepatic Plasmodium vivax and ovale, once erythrocytic forms have been eradicated by a blood schizonticide.
- Elimination of Plasmodium falciparum gametocytes, once erythrocytic forms have been eradicated by a blood schizonticide.
- Contraindications
- Pregnancy
- G-6-P deficiency
- Active rheumatoid arthritis or lupus
- Adverse Effects
- Nausea / vomiting
- Haemolysis
- Methaemoglobinaemia
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