Pregabalin
- OralPregabalinLyrica
Mechanism of Action
- Not fully described, though effects are believed to be due to binding of the α2δ-1 subunit of voltage-gated calcium channels with resultant reduction in nociceptive neurotransmission.
Clinical Use
Indications
- Neuropathic pain.
- Adverse Effects
- Fatigue
- Weight gain
- Dizziness / ataxia