Oral
Prasugrel
Effient
A prodrug that requires enzymatic activation
- Mechanism of Action
- Irreversibly inhibits the binding of adenosine diphosphate (ADP) to platelet P2Y₁₂ receptors, resulting in reduced platelet activation and aggregation.
- Pharmacology
- A pro-drug that requires enzymatic activation.
Clinical Use
- Indications
- Acute coronary syndrome (in conjunction with aspirin)
- Prevention of in-stent thrombosis following percutaneous coronary intervention
- Contraindications
- Active bleeding
- Intracranial haemorrhage
- Adverse Effects
- Haemorrhage.
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