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Pramipexole

 
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 View Topic Outline
  •  
    Oral
    Pramipexole
    Sifrol 

  • Mechanism of Action

  • Acts directly on dopamine D2 and D3 receptors, addressing the severe depletion of dopamine within the striatum pallidum and substantia nigra in Parkinson’s disease.

Clinical Use

  • Indications
  • Parkinson’s disease
  • Restless legs syndrome (off-label)
  • Adverse Effects
  • Fatigue
  • Confusion
  • Dizziness
  • Nausea / vomiting
  • Peripheral oedema
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