Pramipexole
- OralPramipexoleSifrol
Mechanism of Action
- Acts directly on dopamine D2 and D3 receptors, addressing the severe depletion of dopamine within the striatum pallidum and substantia nigra in Parkinson's disease.
Clinical Use
- Indications
- Parkinson's disease
- Restless legs syndrome (off-label)
- Adverse Effects
- Fatigue
- Confusion
- Dizziness
- Nausea / vomiting
- Peripheral oedema