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Drug Guide
 
 

Pioglitazone

 
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 View Topic Outline
  •  
    Oral
    Pioglitazone
    Actos 

  • Mechanism of Action

  • Activates peroxisome proliferator-activated receptor (PPAR), a nuclear receptor that regulates transcription of certain genes involved in glucose and lipid metabolism.

Clinical Use

  • Indications

  • Glycaemic control for severe type II diabetes.
  • Contraindications
  • Heart failure (past or present)
  • Insulin
  • Adverse Effects
  • Headache
  • URTI
  • Myalgia
  • Fluid overload
  • Weight gain
  • Increased risk of bladder cancer
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