- IV / IMPhysostigmine
- Mechanism of Action
- Inhibits acetylcholinesterase, resulting in reduced breakdown of acetylcholine which overcomes anticholinergic agents’ competitive inhibition of nicotinic and muscarinic receptors.
- Crosses the blood-brain barrier, therefore able to counteract the central effects of anticholinergics.
- Anticholinergic toxicity, due to agents such as atropine, scopolamine or benztropine.
- Adverse Effects