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Drug Guide
 
 

Pamidronate

 
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    IV
    Pamidronate
    Aredia 
     
    Used to treat lytic lesions / hypercalcaemia of malignancy
    • Mechanism of Action
    • Structural analogue of pyrophosphate that bind to the resorptive surface of osteoclasts and are internalised. Disruption of key regulatory proteins results in inhibition of osteoclastic function and reduction in bone resorption.
    • Pharmacology

Clinical Use

    • Indications
    • Contraindications
    • Adverse Effects
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