Oxytocin

• Mechanism of Action
• Naturally occurring hormone that binds to oxytocin receptors (G-protein coupled receptors). Causes uterine contraction and milk letdown.

Clinical Use

• • Indications
  • Induction of labour
  • Augmentation of labour
  • Management of the third stage of labour
  • Postpartum haemorrhage
• • Contraindications
  • Foetal distress
  • Vaginal delivery contraindicated
• • Adverse Effects
  • Headache
  • Tachycardia
  • Nausea / vomiting