Login or Register to unlock everything MedSchool has to offer!
Full Drug List
 

#

A

B

C

D

E

F

G

H

I

K

N

O

P

Q

R

S

T

U

V

W

Z

 
 

Oxycodone

  •  
    Oral
    Oxycodone
    Endone, Oxycontin (SR) 
     
    Better tolerated than morphine / codeine
    • Mechanism of Action
    • Acts on opioid receptors (δ, κ and µ) and nociceptin orphanin FQ (NOF) receptors on neuronal cell membranes within the thalamus, diencephalon, midbrain and medulla, resulting in reduced neurotransmitter release.
    • Pharmacology
    • Less histamine release (flushing, itching, rash) and less constipating than natural opioids.

Clinical Use

    • Indication
    • Acute and chronic pain
    • Adverse Effects
    • Nausea / vomiting
    • Constipation
    • Sedation
    • Respiratory depression
    • Diaphoresis
    • Delirium
    • Hypersensitivity – bronchospasm, urticaria
    • Bradycardia
    • Tolerance
    • Dependence
    • Hypogonadism

Associated Adverse Effects
BETA

Feedback