×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Oxaliplatin

 
Bookmark
  •  
    IV
    Oxaliplatin

  • Mechanism of Action

  • An alkylating agent that binds to DNA, causing intrastrand and interstrand crosslinks that change DNA conformation and affect replication.

Clinical Use

  • Indications

  • Certain solid organ and haematologic organ malignancies, as guided by cancer specialists and local guidelines.
  • Adverse Effects
  • Bone marrow suppression ­– leucopaenia, thrombocytopaenia, anaemia
  • Renal dysfunction
  • Nausea / vomiting
  • Elevated LFTs
  • Ototoxicity – tinnitus, hearing loss
  • Transient loss of vision
  • Peripheral neuropathy
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...