Nystatin
- Oral / TopicalNystatinNilstatNot absorbed through skin or mucous membranes
Mechanism of Action
- Binds to ergosterol on the cell membrane, resulting in the formation of pores, leakage of cytoplasmic components and cell death.
Microbiology
- Effective against Candida, Cryptococcus and Aspergillus.
Clinical Use
- Indications
- Topical - superficial, oral or intestinal candidiasis
- Systemic - systemic candidiasis, cryptococcal meningitis, aspergillosis
- Adverse Effects
- With systemic use only.
- Hypersensitivity
- Nephrotoxicity
- Electrolyte abnormalities
- Anaemia
