Drug Guide
 

Noradrenaline

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    CVC
    Noradrenaline

    • Mechanism of Action
    • Directly agonises alpha and beta adrenoceptors, resulting in stimulation of sympathetic activity.
    • Pharmacology
    • Greater affinity for alpha than beta adrenoceptors, resulting in greater vasoconstriction than adrenaline.

Clinical Use

    • Indication
    • Profound hypotension, especially in the case of distributive shock.
    • Adverse Effects
    • Anxiety / restlessness / tremor
    • Tachycardia
    • Dyspnoea
    • Dizziness
    • Cold peripheries
    • Nausea / vomiting
    • Ischaemic injury
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