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Drug Guide
 
 

Nilotinib

 
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    Oral
    Nilotinib
    Tasigna 
     
    Binds both active & inactive conformation of Bcr-Abl kinase, resulting in reduced resistance
    • Mechanism of Action
    • Inhibits the Bcr-Abl tyrosine kinase as well as the stem cell receptor factor (cKIT) and several other receptor tyrosine kinases.

Clinical Use

    • Indication
    • Philadelphia chromosome positive chronic myeloid leukaemia in the chronic phase or with resistance or intolerance to imatinib
    • Adverse Effects
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