Nicorandil
- OralNicorandilIkorel
Mechanism of Action
- Stimulates opening of ATP-dependant potassium channels in vascular smooth muscle, resulting in arterial dilatation and reduced afterload. Also has nitrate activity, resulting in venous dilatation and reduced preload.
Clinical Use
Indications
- Stable angina pectoris.
- Adverse Effects
- Headache
- Lethargy
- Tachycardia
- Nausea / vomiting