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Nebivolol

  •  
    Oral
    Nebivolol
    Nebilet 
     
    β1 antagonism, as well as vasodilatation due to increased endothelial NO release
    • Mechanism of Action
    • Selectively and competitively inhibit the action of adrenaline and noradrenaline on β1, resulting in suppression of the sympathetic nervous system.

      Also stimulates release of nitric oxide (NO) from the endothelium, resulting in vasodilatation.

Clinical Use

    • Indication
    • Hypertension – second-line therapy, especially indicated for patients with stable angina or post MI.
      Stable heart failure
    • Contraindications
    • Asthma
    • Decompensated heart failure
    • AV block
    • Adverse Effects
    • Fatigue / headache
    • Bradycardia
    • Postural hypotension
    • Nausea / vomiting / diarrhoea

Potential Indications
BETA

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