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Natalizumab

  •  
    IV
    Natalizumab
    Tysabri 
    • Mechanism of Action
    • Monoclonal antibody toward leucocyte adhesion molecules, resulting in slowed entry of T cells into the CNS.

Clinical Use

    • Indication
    • Relapsing-remitting multiple sclerosis (MS).
    • Contraindications
    • Other immunomodulatory agents
    • Immunocompromised patients
    • Adverse Effects
    • Progressive multifocal leukencephalopathy (PML)
    • Headache
    • Fatigue
    • Arthralgia
    • Increased risk of infection

Potential Indications
BETA

Multiple Sclerosis

Associated Adverse Effects
BETA

Progressive Multifocal Leukencephalopathy
Progressive Multifocal Leukencephalopathy
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