IV
N-Acetylcysteine
Acetadote
Mechanism of Action
- Provides cysteine for use in the synthesis of glutathione, which facilitates metabolism of the toxic paracetamol metabolite N-acetyl-p-benzoquinoneimine.
Clinical Use
Indications
- Severe paracetamol / acetaminophen overdose.
- Adverse Effects
- Hypersensitivity - rash, oedema, bronchospasm, anaphylaxis
- Nausea / vomiting
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