Drug Guide
 

N-Acetylcysteine

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    IV
    N-Acetylcysteine
    Acetadote 
    • Mechanism of Action
    • Provides cysteine for use in the synthesis of glutathione, which facilitates metabolism of the toxic paracetamol metabolite N-acetyl-p-benzoquinoneimine.

Clinical Use

    • Indication
    • Severe paracetamol / acetaminophen overdose.
    • Adverse Effects
    • Hypersensitivity – rash, oedema, bronchospasm, anaphylaxis
    • Nausea / vomiting
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