Mycophenolate Mofetil
- Oral / IVMycophenolate MofetilCellCept, Myfortic
- Mechanism of Action
- A prodrug of mycophenolic acid (MPA), a non-competitive, reversible inhibitor of inosine monophosphate dehydrogenase (IMPD). IMPD is a key enzyme in the synthesis of guanosine triphosphate; T cells and B cells are critically dependent on this pathway and thus its inhibition results in impaired lymphocyte proliferation.
Clinical Use
- Indications
- Adverse Effects