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Drug Guide



    • Mechanism of Action
    • Inhibits the activity of monoamine oxidase, responsible for breakdown of monoamines. Inhibition results in increased synaptic noradrenaline, dopamine and serotonin.

Clinical Use

    • Indication
    • Depression refractory to more commonly used medications.
    • Contraindications
    • Not for concurrent use with selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs) or tricyclic antidepressants (TCAs).
    • Adverse Effects
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