Misoprostol
- OralMisoprostolGyMisoGiven 36 - 48 hours after mifepristone
Mechanism of Action
- Synthetic prostaglandin E1, which stimulates myometrial contraction and expulsion of foetal tissue.
Clinical Use
- Indications
- Medical abortion
- Prevention and treatment of NSAID-induced gastritis
- Contraindications
- Bleeding disorder / anticoagulants
- Uncertainty about age of pregnancy
- Suspected ectopic pregnancy
- Adverse Effects
- Uterine contractions
- Per vaginal bleeding
- Headache
- Dizziness
- Nausea / vomiting / diarrhoea