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Drug Guide

Mifepristone (RU486)

    Mifepristone (RU486)
    Given initially to prepare the genitourinary tract
    • Mechanism of Action
    • Competitively inhibit the action of progesterone and glucocorticoid on their receptors. Results in endometrial degeneration, cervical dilatation, prostaglandin release, reduced progesterone release and reduced β-HCG production.

Clinical Use

    • Indication
    • Preparation of the genital tract for medical abortion.
    • Contraindications
    • Adverse Effects
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