Midazolam

• Mechanism of Action
• Positively modulates GABA_A receptors (BZ1 and BZ2), augmenting the inhibitory effects of the GABA neurotransmitter.

Clinical Use

• • Indications
  • Acute anxiety
  • Tranquilization – in the acute psychiatric settingSedation - for short surgical procedures or intensive care
  • Status epilepticus
• • Adverse Effects
  • Drowsiness
  • Hypersalivation
  • Muscle weakness
  • Vertigo